Next Generation Sequencing

A big welcome to “Bioinformatics: Introduction and Methods” from Peking University! In this MOOC you will become familiar with the concepts and computational methods in the exciting interdisciplinary field of bioinformatics and their applications in biology, the knowledge and skills in bioinformatics you acquired will help you in your [...]

Perform RNA-Seq, ChIP-Seq, and DNA methylation data analyses, using open source software, including R and Bioconductor. We will explain how to perform the standard processing and normalization steps, starting with raw data, to get to the point where one can investigate relevant biological questions. [...]

The structure, annotation, normalization, and interpretation of genome scale assays. We begin with an introduction to the biology, explaining what we measure and why. Then we focus on the two main measurement technologies: next generation sequencing and microarrays. We then move on to describing how raw data and experimental [...]

Understand new and established genomic sequencing technologies, and how to apply them in clinical practice. Powerful new technologies have been driving forward immense and exciting changes in clinical practice. The days of peering down the microscope to detect chromosome abnormalities are gone, replaced by chromosome analysis at the genomic [...]

Learn how molecular genetic techniques are used to identify the genetic factors that contribute to the development of disease. Powerful new technologies have been driving forward immense and exciting changes in clinical practice.

This course presents clinicians and digital health enthusiasts with an overview of the data revolution in medicine and how to exploit it for research and in the clinic. The course will not make you a bioinformatician but will introduce the main concepts, tools, algorithms, and databases in this [...]

Learn about the role of clinical bioinformaticians in healthcare and how their work is helping to realise the genomics revolution. This free online course aims to raise awareness amongst healthcare professionals of the role of Clinical Bioinformatics and Genomics in healthcare today.

Learn how to use existing tools and pipelines to analyze next generation sequencing (NGS) data. Are you interested in analyzing biological datasets but don’t have a strong computational background? Do you want to focus on the biology and learn how to use modern best-practice pipelines that use existing tools? [...]